The Chennai to Manipal bus route covers approximately 761 kms and takes about 15 hrs 48 mins. A total of 2 direct buses operated by 1 bus operators run on this route. The first bus departs at 14:15, and the last bus leaves at 17:00.
Major boarding points in Chennai include Ashok Pillar, Ekkattuthangal, Guindy, Kanchipuram, Karappakkam, Koyambedu, Madhya Kailash, Maduravoyal, Navalur, Periamet, while common drop locations in Manipal are Indrali Busstop, Mgm College, Tiger Circle.
RTC and private operators such as Bharathi Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 1500 - INR 1600.00 depending on the bus type and features.



