The Chennai to Salem bus route covers approximately 344 kms and takes about 6 hrs 44 mins. A total of 373 direct buses operated by 136 bus operators run on this route. The first bus departs at 00:15, and the last bus leaves at 23:55.
Major boarding points in Chennai include Adyar, Alandur, Ambattur, Aminjikarai, Anna Nagar, Anna University, Arumbakkam, Ashok Pillar, Avadi, Central Railway Station, while common drop locations in Salem are Ammapet Bypass Road, Ariyanur, Attur, Avr Roundana, Ayodhiyapatinam, Deevattipatti, Karipatti Bypass, Kondalampatti, Krishnagiri Bypass, Magudanchavadi.
RTC and private operators such as SRL Travels, Jayalakshmi Bus, S R T, VHB Travels, MRS Transport offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 349 - INR 5199.00 depending on the bus type and features.










