The Kayamkulam to Palakkad bus route covers approximately 237 kms and takes about 6 hrs 5 mins. A total of 48 direct buses operated by 12 bus operators run on this route. The first bus departs at 00:30, and the last bus leaves at 23:50.
Major boarding points in Kayamkulam include Central Bus Stand Cbt, Kaniyapuram,, Others, while common drop locations in Palakkad are Chanda Nagar, Chandranagar, Chandranagar Bypass, Palakkad Bypass, Vadakkancherry, Walaiyar.
RTC and private operators such as Surya Connect, Kerala lines , Kallada Travels (Suresh Kallada) offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 319 - INR 2000.00 depending on the bus type and features.



