The Salem to Ongole bus route covers approximately 567 kms and takes about 10 hrs 33 mins. A total of 9 direct buses operated by 7 bus operators run on this route. The first bus departs at 17:00, and the last bus leaves at 21:30.
Major boarding points in Salem include Avr Roundana, Salem New Bus Stand, Thiruvagoundanur, while common drop locations in Ongole are Mangamuru, RTC Bus Stand.
RTC and private operators such as Kallada Travels (Suresh Kallada), Sri Tulasi Tours and Travels, Orange Tours And Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 960 - INR 2405.00 depending on the bus type and features.



