The Salem to Chennai bus route covers approximately 343 kms and takes about 6 hrs 23 mins. A total of 406 direct buses operated by 159 bus operators run on this route. The first bus departs at 00:05, and the last bus leaves at 23:59.
Major boarding points in Salem include Ammapet Bypass Road, Ariyanur, Attur, Avr Roundana, Ayodhiyapatinam, Deevattipatti, Karipatti Bypass, Kondalampatti, Krishnagiri Bypass, Magudanchavadi, while common drop locations in Chennai are Adyar, Airport Bus Stand, Alandur, Ambattur, Aminjikarai, Anna Nagar, Anna University, Arumbakkam, Ashok Pillar, Avadi.
RTC and private operators such as SRL Travels, Jayalakshmi Bus, S R T, VHB Travels, SMS Tours and Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 338 - INR 5199.00 depending on the bus type and features.










