The Nellore to Khammam bus route covers approximately 352 kms and takes about 7 hrs 31 mins. A total of 10 direct buses operated by 9 bus operators run on this route. The first bus departs at 00:20, and the last bus leaves at 23:15.
Major boarding points in Nellore include Atmakur Bus Stand, Ayyappa Gudi,nellore, Bus Stand, Mini Bypass, Venkatachalam Toll Plaza, while common drop locations in Khammam are Ashok Nagar, Begumpet.
RTC and private operators such as Abhishek Bus offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 656 - INR 4500.00 depending on the bus type and features.



