The Payyoli to Thrissur bus route covers approximately 157 kms and takes about 3 hrs 52 mins. A total of 38 direct buses operated by 17 bus operators run on this route. The first bus departs at 00:05, and the last bus leaves at 23:59.
Major boarding points in Payyoli include Koyilandi, Kozhikode, Payyoli, Vadakara, while common drop locations in Thrissur are Amala Medical College, Thrissur, KSRTC Bus Stand, Kadavanthara, Others.
RTC and private operators such as Azul Transports Private Limited offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 599 - INR 1500.00 depending on the bus type and features.



