The Nagercoil to Thiruvananthapuram bus route covers approximately 78 kms and takes about 1 hrs 50 mins. A total of 40 direct buses operated by 10 bus operators run on this route. The first bus departs at 03:45, and the last bus leaves at 20:55.
Major boarding points in Nagercoil include Kavalkinaru, Panagudi, Thakkalai, Thovalai, Vadasery Omni Bus Stand, Vellamadam, while common drop locations in Thiruvananthapuram are Attingal, Balaramapuram, Chakka Pass, East Thampanoor, Infosys Campus, Kaniyapuram,, Kazhakootam, Neyyatinkare, Others, Pappanamcode, Thiruvananthapuram.
RTC and private operators such as VKV Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 88 - INR 5038.00 depending on the bus type and features.



