The Palladam to Tirunelveli bus route covers approximately 310 kms and takes about 5 hrs 59 mins. A total of 31 direct buses operated by 22 bus operators run on this route. The first bus departs at 00:20, and the last bus leaves at 23:59.
Major boarding points in Palladam include Palladam, Sulur, while common drop locations in Tirunelveli are KTC Nagar, Kayathar, Others, Papanasam, Passport Seva Kendra, Sankarnagar, Thatchanallur, Tirunelveli bypass, Udayarpatti, Vannarpettai.
RTC and private operators such as Jai Vishnu Travels, Sri Selvam Travels (PSP), PSS Transport, SPS Travels India, KNT Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 325 - INR 3000.00 depending on the bus type and features.



