The Hosur to Karaikudi bus route covers approximately 375 kms and takes about 7 hrs 55 mins. A total of 20 direct buses operated by 15 bus operators run on this route. The first bus departs at 20:00, and the last bus leaves at 23:25.
Major boarding points in Hosur include Bus Stand, while common drop locations in Karaikudi are Nemathanpatti, New Bus Stand, Sriram Nagar.
RTC and private operators such as ANNAI TRAVELS, RKT Tours and Travels, Rithish Travels, Vairam Travels, AAHHAA TOURIST offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 500 - INR 1999.00 depending on the bus type and features.



